VIP-10mg
Peptide: VIP (Vasoactive Intestinal Peptide)
Bottle Dose: 10mg
Origin & Structure
VIP is a 28–amino acid neuropeptide, part of the secretin/glucagon family.
Naturally produced in the gut, pancreas, and brain, especially in the hypothalamus and enteric nervous system.
Potential Benefits of VIP (Research-Based)
1. Neuroprotection & Brain Health
Enhances neuronal survival and protects against excitotoxic damage
Regulates circadian rhythm and sleep-wake cycles
May improve memory and cognitive resilience
2. Immune Modulation
Suppresses excessive inflammation and autoimmunity
Enhances tolerance and regulatory T-cell activity
Being explored for autoimmune conditions (RA, IBD, MS)
3. Anti-Inflammatory & Healing
Protects mucosal barriers (gut, lungs)
Reduces oxidative stress and tissue injury
May accelerate wound healing and tissue repair
4. Cardiovascular & Pulmonary Support
Potent vasodilator → improves circulation and reduces vascular resistance
Pulmonary benefits: bronchodilation, improved oxygenation
Studied for pulmonary hypertension and asthma
5. Gastrointestinal Function
Stimulates intestinal secretion and motility
Protects gut lining integrity
Potential applications in IBS, IBD, and leaky gut
Key Caveats
Short Half-Life: Native VIP degrades quickly in circulation; analogs or formulations are often required for stability.
Potency: Works at very low concentrations; improper dosing can cause GI upset or hypotension.
Limited Human Trials: Most clinical use remains experimental (except a few orphan-drug studies, e.g., Aviptadil for pulmonary hypertension and COVID-related ARDS).
Systemic Effects: Because it is a vasodilator and gut motility stimulator, side effects may include flushing, loose stools, or low blood pressure.
In summary: VIP is a multifunctional neuropeptide that regulates inflammation, immunity, vasodilation, and neuroprotection. Its therapeutic promise spans autoimmunity, pulmonary disease, gut health, and neurodegeneration, though stability and delivery remain key challenges.