SLU-PP-332 is an experimental small molecule that acts as a potent REV-ERB agonist, targeting core components of the circadian rhythm and metabolic regulation. By activating REV-ERBα and REV-ERBβ receptors, SLU-PP-332 helps suppress lipogenesis (fat storage), increase mitochondrial activity, and boost fat oxidation, particularly during the body’s natural fasting state. It effectively enhances energy expenditure without increasing food intake, making it a promising agent for non-stimulant, round-the-clock fat loss. Additionally, it supports improved sleep-wake cycles, reduced inflammation, and better metabolic flexibility, which are key to long-term body composition improvements.

Top 4 Peptides to Stack Synergistically with SLU-PP-332 for Fat Loss:

• CJC-1295 + Ipamorelin – enhances growth hormone secretion, amplifying fat breakdown and muscle preservation while supporting nighttime recovery—synergistic with SLU-PP-332’s circadian modulation.

• AOD-9604 – targets stubborn fat stores directly through increased lipolysis, providing a complementary mechanism to SLU-PP-332’s mitochondrial-driven energy burn.

• Tesamorelin – excels at reducing visceral (abdominal) fat and supports cognitive function, pairing well with SLU-PP-332’s anti-inflammatory and metabolic benefits.

• 5-Amino-1MQ – increases cellular energy output and reduces fat accumulation via NNMT inhibition, making it a strong metabolic enhancer alongside SLU-PP-332’s circadian-based fat-loss action.